1990-1995

  1. S.P.C. Cole, H.F. Downes, S.E.L. Mirski and D.R. Clements. Alterations in glutathione and glutathione-related enzymes in a multidrug resistant small cell lung cancer cell line. Molec.Pharmacol. 37: 192-197 (1990).
  2. S.P.C. Cole, S.A. Mohamdee and S.E.L. Mirski. A monoclonal antibody detecting a cell surface epitope on some drug resistant human tumour cell lines. Br. J. Cancer 62: 14-16 (1990).
  3. S.P.C. Cole. Patterns of cross-resistance in a multidrug resistant small cell lung carcinoma cell line. Cancer Chemother. Pharmacol. 26: 250-256 (1990).
  4. S.P.C. Cole. The legacy of Terry Fox. Queen's Quarterly 97: 253-276 (1990).
  5. B.G. Campling, J. Pym, H. Baker, S.P.C. Cole and M. Lam. Chemosensitivity testing of small cell lung cancer using the MTT assay. Br. J. Cancer 63: 75-83 (1991).
  6. S.P.C. Cole, B.M.T. Campigotto, J.G. Johnson and B.E. Elliott. Differential growth inhibition and enhancement of major histocompatibility complex class I antigen expression by interferons in a small cell lung cancer cell line and its doxorubicin-selected multidrug-resistant variant. Cancer Immunol. Immunother. 33: 274-277 (1991).
  7. S.P.C. Cole, E.R. Chanda, F.P. Dicke, J.H. Gerlach and S.E.L. Mirski. Non-P-glycoprotein-mediated multidrug resistance in a small cell lung cancer cell line: Evidence for decreased susceptibility to drug-induced DNA damage and reduced levels of topoisomerase II. Cancer Res. 51: 3345-3352 (1991).
  8. S.E.L. Mirski and S.P.C. Cole. Multidrug resistance-associated antigens on drug-sensitive and -resistant human tumour cell lines. Br. J. Cancer 64: 15-22 (1991).
  9. M.L. Slovak, S.E.L. Mirski, S.P.C. Cole, J.H. Gerlach, K.H. Yohem and J.M. Trent. Tumorigenic multidrug resistant HT1080 cells do not overexpress receptors for epidermal growth factor. Br. J. Cancer 64: 296-298 (1991).
  10. S.P.C. Cole. The Merck-Frosst Award. Multidrug resistance in small cell lung cancer. Can. J. Physiol. Pharmacol. 70: 313-329 (1992). (invited and peer-reviewed).
  11. S.P.C. Cole, M.J. Pinkoski, G. Bhardwaj and R.G. Deeley. Elevated expression of annexin II (lipocortin II, p36) in a multidrug resistant small cell lung cancer cell line. Br. J. Cancer 65: 498-502 (1992).
  12. S.P.C. Cole. Drug resistance and lung cancer. In, Cancer: Concept to Clinic (ed. J. Wood), Vol. 1, pp. 15-21, Medical Publishing Enterprises, Fairlawn, N.J. (1992). (invited)
  13. B. Savas, S.P.C. Cole, T.F. Akoglu and H.F. Pross. P-glycoprotein-mediated multidrug resistance and cytotoxic effector cells. Nat. Immun. 11: 177-192 (1992).
  14. J.E. Gervasoni, Jr., R.N. Taub, M.T. Yu, D. Warburton, M. Sabbath, D.L. Coppock, J. D'Alessandri, S. Krishna, M. Rosado, M.A. Baker, J. Lutzky, E.R. Chanda, J.H. Gerlach, M.J. Pinkoski, S.P.C. Cole and A.A. Hindenburg. Homogeneously staining region in anthracycline-resistant HL-60/AR cells not associated with MDR1 amplification. Cancer Res. 52: 5244-5249 (1992).
  15. S.P.C. Cole, G. Bhardwaj, J.H. Gerlach, J.E. Mackie, C.E. Grant, K.C. Almquist, A.J. Stewart, E.U. Kurz, A.M.V. Duncan and R.G. Deeley. Overexpression of a transporter gene in a multidrug resistant human lung cancer cell line. Science 258: 1650-1654 (1992).
  16. S.P.C. Cole and R.G. Deeley. Multidrug resistance-associated protein: sequence correction. Science 260: 879 (1993).
  17. K.A. Krebes, S.E.L. Mirski, H.F. Pross and S.P.C. Cole. Peripheral blood mononuclear cells express antigens associated with multidrug resistance in a small cell lung cancer cell line. Anticancer Res. 13: 317-322 (1993).
  18. B.G. Campling, K.A. Baer, H.M. Baker, Y.-M. Lam and S.P.C. Cole. Do glutathione and related enzymes play a role in drug resistance in small cell lung cancer? Br. J. Cancer 68: 327-335 (1993).
  19. M.L. Slovak, J.P. Ho, G. Bhardwaj, E.U. Kurz, R.G. Deeley and S.P.C. Cole. Localization of a novel multidrug resistance-associated gene in the HT1080/DR4 and H69AR human tumor cell lines. Cancer Res. 53: 3221-3225 (1993).
  20. J. Jirsch, R.G. Deeley, S.P.C. Cole, A.J. Stewart and D. Fedida. Inwardly rectifying K+ channels and volume-regulated anion channels in multidrug resistant small cell lung cancer cells. Cancer Res. 53: 4156-4160 (1993).
  21. S.E.L. Mirski, C.D. Evans, K.C. Almquist, M.L. Slovak and S.P.C. Cole. Altered topoisomerase II in a drug resistant small cell lung cancer cell line selected in VP-16. Cancer Res. 53: 4866-4873 (1993).
  22. C.E. Grant, G. Valdimarsson, D.R. Hipfner, K.C. Almquist, S.P.C. Cole and R.G. Deeley. Overexpression of multidrug resistance-associated protein (MRP) increases resistance to natural product drugs. Cancer Res. 54: 357-361 (1994).
  23. P.W. Feldhoff, S.E.L. Mirski, S.P.C. Cole and D.M.M. Sullivan. Altered subcellular distribution of topoisomerase II in a drug resistant human small cell lung cancer cell line. Cancer Res. 54: 756-762 (1994).
  24. J.R. Zalcberg, X.F. Hu, D.M. Wall, S. Mirski, S. Cole, G. Nadalin, M.D. Luise, J.D. Parkin, V. Vrazas, L. Campbell and P. Kantharidis. Cellular and karyotypic characterization of two doxorubicin resistant cell lines isolated from the same parental human leukemia cell line. Int. J. Cancer 57: 522-528 (1994).
  25. B.J. Kuss, R.G. Deeley, S.P.C. Cole, C.L. Willman, K.J. Kopecky, S.R. Wolman, H.J. Eyre, S.A. Lane, J.K. Nancarrow, S.A. Whitmore and D.F. Callen. Deletion of gene for multidrug resistance in acute myeloid leukaemia with inversion in chromosome 16: prognostic implications. Lancet 343: 1531-1534 (1994).
  26. C.D. Evans, S.E.L. Mirski, M.K. Danks and S.P.C. Cole. Reduced levels of topoisomerase II and in a multidrug resistant lung cancer cell line. Cancer Chemother. Pharmacol. 34: 242-248 (1994).
  27. J.D. Jirsch, D.W. Loe, S.P.C. Cole, R.G. Deeley and D. Fedida. ATP is not required for anion current activated by cell swelling in multidrug-resistant lung cancer cells. Amer. J. Physiol. 267: 688-699 (1994).
  28. S.P.C. Cole, K.E. Sparks, K. Fraser, D.W. Loe, C.E. Grant, G.M. Wilson and R.G. Deeley. Pharmacological characterization of multidrug resistant MRP-transfected human tumor cells. Cancer Res. 54: 5902-5910 (1994).
  29. I. Leier, G. Jedlitschky, U. Buchholz, S.P.C. Cole, R.G. Deeley and D. Keppler. The MRP gene encodes an ATP-dependent export pump for leukotriene C4 and structurally related conjugates. J. Biol. Chem. 269: 27807-27810 (1994).
  30. D.R. Hipfner, S.D. Gauldie, R.G. Deeley and S.P.C. Cole. Detection of the Mr 190,000 multidrug resistance protein, MRP, with monoclonal antibodies. Cancer Res. 54: 5788-5792 (1994).
  31. T. Sumizawa, Y. Chuman, H. Sakamoto, K. Iemura, K.C. Almquist, R.G. Deeley, S.P.C. Cole and S.-i. Akiyama. Non-P-glycoprotein-mediated multidrug resistant human KB cells selected in medium containing Adriamycin, cepharanthine and mezerein. Som. Cell Mol. Gen. 20: 423-435 (1994).
  32. K.C. Almquist, D.W. Loe, D.R. Hipfner, J.E. Mackie, S.P.C. Cole* and R.G. Deeley. Characterization of the Mr 190,000 multidrug resistance protein (MRP) in drug-selected and transfected human tumor cells. Cancer Res. 55: 102-110 (1995). * corresponding author
  33. I. Brock, D.R. Hipfner, B.E. Nielsen, P.B. Jensen, R.G. Deeley, S.P.C. Cole and M. Sehested. Sequential co-expression of the multidrug resistance genes, MRP and mdr1 and their products in VP-16 (etoposide) selected H69 small cell lung cancer cells. Cancer Res. 55: 459-462 (1995).
  34. S.E.L. Mirski and S.P.C. Cole. Cytoplasmic localization of a mutant Mr 160,000 topoisomerase II is associated with the loss of putative bipartite nuclear localization signals in a drug resistant human lung cancer cell line. Cancer Res. 55: 2129-2134 (1995).
  35. S. Hasegawa, T. Abe, S. Naito, S. Kotoh, J. Kumazawa, D.R. Hipfner, R.G. Deeley, S.P.C. Cole and M. Kuwano. Expression of multidrug resistance-associated protein (MRP), MDR1 and DNA topoisomerase II in human multidrug resistant bladder cancer cell lines. Br. J. Cancer 71: 907-913 (1995).
  36. J.R. Dimmock, P. Kumar, J.W. Quail, U. Pugazhenthi, J. Yang, M. Chen, R.S. Reid, T.M. Allen, G.Y. Kao, S.P.C. Cole, G. Batist, J. Balzarini and E. De Clercq. Synthesis and cytotoxic evaluation of some styryl ketones and related compounds. Eur. J. Med. Chem. 30: 209-217 (1995).
  37. M.L. Slovak, J.P. Ho, S.P.C. Cole, R.G. Deeley, L. Greenberger, E.G.E. deVries, H.J. Broxterman, G.L. Scheffer and R.J. Scheper. The LRP gene encoding a major vault protein associated with drug resistance maps proximal to MRP on chromosome 16: evidence that chromosome breakage plays a key role in MRP or LRP gene amplification. Cancer Res. 55: 4214-4219 (1995).