M.F. Rosenberg, Q. Mao, A. Holzenburg, R.C. Ford, R.G. Deeley and S.P.C. Cole. The structure of the multidrug resistance protein 1 (MRP1/ABCC1): crystallization and single-particle analysis. J. Biol. Chem. 276: 16076-16082 (2001).
D. Zhang, S.P.C. Cole and R.G. Deeley. Identification of an amino acid residue in Multidrug Resistance Protein (MRP)1 critical for conferring resistance to anthracyclines. J. Biol. Chem. 276: 13231-13239 (2001).
E.M. Leslie, Q. Mao, C.J. Oleschuk, R.G. Deeley and S.P.C. Cole. Modulation of Multidrug Resistance Protein 1 (MRP1/ABCC1) transport and ATPase activities by interaction with dietary flavonoids. Mol. Pharmacol. 59: 1171-1180 (2001).(Among top ten articles viewed in Mol. Pharmacol. 2005).
K. Ito, S.L. Olsen, W. Qiu, R.G. Deeley and S.P.C. Cole. Mutation of a single conserved tryptophan in multidrug resistance protein 1 (MRP1/ABCC1) results in loss of drug resistance and selective loss of organic anion transport. J. Biol. Chem. 276: 15616-15624 (2001).
L.C. Young, B.G. Campling, S.P.C. Cole, R.G. Deeley and J.H. Gerlach. Multidrug resistance proteins MRP3, MRP1 and MRP2 in lung cancer: correlation of protein levels with drug response and messenger RNA levels. Clin. Cancer Res. 7: 1798-1804 (2001).
R. Zirngibl, D. Schulze, S. Mirski, S.P.C. Cole and P. Greer. Subcellular localization analysis of the closely related Fps/Fes and Fer protein-tyrosine kinases suggests a distinct role for Fps/Fes in vesicular trafficking. Exp. Cell Res. 266: 87-94 (2001).
E.M. Leslie, R.G. Deeley and S.P.C. Cole. Toxicological relevance of the multidrug resistance protein 1, MRP1 (ABCC1) and related transporters. Toxicology 167: 3-23 (2001).(In TOP 40 of articles cited in Toxicology 2001-2006).
E.M. Leslie, K. Ito, P. Upadhyaya, S.S. Hecht, R.G. Deeley and S.P.C. Cole. Transport of the -O-glucuronide conjugate of the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) by the multidrug resistance protein 1 (MRP1/ABCC1): Requirement for glutathione or a non-sulfur-containing analog. J. Biol. Chem. 276: 27846-27854 (2001).
E.U. Kurz, S.P.C. Cole and R.G. Deeley. Identification of DNA-protein interactions in the 5' flanking and 5' untranslated regions of the human multidrug resistance protein (MRP1) gene: Evaluation of a putative antioxidant response element/AP-1 binding site. Biochem. Biophys. Res. Commun. 285: 981-990 (2001).
D. Zhang, S.P.C. Cole and R.G. Deeley. Identification of a non-conserved amino acid residue in Multidrug Resistance Protein (MRP) 1 important for determining substrate specificity: evidence for functional interaction between transmembrane helices 14 and 17. J. Biol. Chem. 276: 34966-34974 (2001).
K. Ito, C.J. Oleschuk, C. Westlake, M.Z. Vasa, R.G. Deeley and S.P.C. Cole. Mutation of Trp1254 in the multispecific organic anion transporter, multidrug resistance protein 2 (MRP2) (ABCC2), alters substrate specificity and results in loss of methotrexate transport activity. J. Biol. Chem. 276: 38108-38114 (2001).
Y.M. Qian, W. Qiu, M. Gao, C.J. Westlake, S.P.C. Cole and R.G. Deeley. Characterization of binding of leukotriene C4 by human multidrug resistance protein 1: evidence of differential interactions with NH2- and COOH-proximal halves of the protein. J. Biol. Chem. 276: 38636-38644 (2001).
S. Conrad, H-M. Kauffmann, K-i. Ito, R. Deeley, S.P.C. Cole and D. Schrenk. Identification of human multidrug resistance protein 1 (MRP1) mutations and characterization of a G671V substitution. J. Hum. Genet. 46: 656-663 (2001).