2001

  1. Y.M. Qian, W.C. Song, H.R. Cui, S.P.C. Cole and R.G. Deeley. Glutathione stimulates sulfated estrogen transport by multidrug resistance protein 1. J. Biol. Chem. 276: 6404-6411 (2001).
  2. M.F. Rosenberg, Q. Mao, A. Holzenburg, R.C. Ford, R.G. Deeley and S.P.C. Cole. The structure of the multidrug resistance protein 1 (MRP1/ABCC1): crystallization and single-particle analysis. J. Biol. Chem. 276: 16076-16082 (2001).
  3. D. Zhang, S.P.C. Cole and R.G. Deeley. Identification of an amino acid residue in Multidrug Resistance Protein (MRP)1 critical for conferring resistance to anthracyclines. J. Biol. Chem. 276: 13231-13239 (2001).
  4. E.M. Leslie, Q. Mao, C.J. Oleschuk, R.G. Deeley and S.P.C. Cole. Modulation of Multidrug Resistance Protein 1 (MRP1/ABCC1) transport and ATPase activities by interaction with dietary flavonoids. Mol. Pharmacol. 59: 1171-1180 (2001). (Among top ten articles viewed in Mol. Pharmacol. 2005).
  5. K. Ito, S.L. Olsen, W. Qiu, R.G. Deeley and S.P.C. Cole. Mutation of a single conserved tryptophan in multidrug resistance protein 1 (MRP1/ABCC1) results in loss of drug resistance and selective loss of organic anion transport. J. Biol. Chem. 276: 15616-15624 (2001).
  6. L.C. Young, B.G. Campling, S.P.C. Cole, R.G. Deeley and J.H. Gerlach. Multidrug resistance proteins MRP3, MRP1 and MRP2 in lung cancer: correlation of protein levels with drug response and messenger RNA levels. Clin. Cancer Res. 7: 1798-1804 (2001).
  7. R. Zirngibl, D. Schulze, S. Mirski, S.P.C. Cole and P. Greer. Subcellular localization analysis of the closely related Fps/Fes and Fer protein-tyrosine kinases suggests a distinct role for Fps/Fes in vesicular trafficking. Exp. Cell Res. 266: 87-94 (2001).
  8. E.M. Leslie, R.G. Deeley and S.P.C. Cole. Toxicological relevance of the multidrug resistance protein 1, MRP1 (ABCC1) and related transporters. Toxicology 167: 3-23 (2001). (In TOP 40 of articles cited in Toxicology 2001-2006).
  9. E.M. Leslie, K. Ito, P. Upadhyaya, S.S. Hecht, R.G. Deeley and S.P.C. Cole. Transport of the -O-glucuronide conjugate of the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) by the multidrug resistance protein 1 (MRP1/ABCC1): Requirement for glutathione or a non-sulfur-containing analog. J. Biol. Chem. 276: 27846-27854 (2001).
  10. E.U. Kurz, S.P.C. Cole and R.G. Deeley. Identification of DNA-protein interactions in the 5' flanking and 5' untranslated regions of the human multidrug resistance protein (MRP1) gene: Evaluation of a putative antioxidant response element/AP-1 binding site. Biochem. Biophys. Res. Commun. 285: 981-990 (2001).
  11. D. Zhang, S.P.C. Cole and R.G. Deeley. Identification of a non-conserved amino acid residue in Multidrug Resistance Protein (MRP) 1 important for determining substrate specificity: evidence for functional interaction between transmembrane helices 14 and 17. J. Biol. Chem. 276: 34966-34974 (2001).
  12. K. Ito, C.J. Oleschuk, C. Westlake, M.Z. Vasa, R.G. Deeley and S.P.C. Cole. Mutation of Trp1254 in the multispecific organic anion transporter, multidrug resistance protein 2 (MRP2) (ABCC2), alters substrate specificity and results in loss of methotrexate transport activity. J. Biol. Chem. 276: 38108-38114 (2001).
  13. Y.M. Qian, W. Qiu, M. Gao, C.J. Westlake, S.P.C. Cole and R.G. Deeley. Characterization of binding of leukotriene C4 by human multidrug resistance protein 1: evidence of differential interactions with NH2- and COOH-proximal halves of the protein. J. Biol. Chem. 276: 38636-38644 (2001).
  14. S. Conrad, H-M. Kauffmann, K-i. Ito, R. Deeley, S.P.C. Cole and D. Schrenk. Identification of human multidrug resistance protein 1 (MRP1) mutations and characterization of a G671V substitution. J. Hum. Genet. 46: 656-663 (2001).