2014

  1. S.H. Iram and S.P.C. Cole. Differential functional rescue of Lys513 and Lys516 processing mutants of MRP1 (ABCC1) by chemical chaperones reveals different domain-domain interactions of the transporter. Biochim. Biophys. Acta 1838: 756-765 (2014).
  2. S.P.C. Cole. Targeting multidrug resistance protein 1 (MRP1, ABCC1): Past, present and future. Annu. Rev. Pharmacol. Toxicol. 54: 95-117 (2014). (invited review, impact factor 21.6).
  3. J. Park, J-O. Kwak, B. Riederer, U. Seidler, S.P.C. Cole, H.J. Lee and M.G. Lee. Na+/H+ exchanger regulatory factor 3 is critical for multidrug resistance protein 4-mediated drug efflux in the kidney. J. Am. Soc. Nephrol. 25: 727-736 (2014). [Highlighted in Nat. Rev. Nephrol. 10: 183 (2014)].
  4. L. Cheung, C.L. Flemming, F. Watt, N. Masada, D.M. Yu, T. Huynh, G. Conseil, A. Tivnan, A. Polinsky, A.V. Gudkov, M.A. Munoz, A. Vishvanath, D.M. Cooper, M.J. Henderson, S.P.C. Cole, J.I. Fletcher, M. Haber and M.D. Norris. High-throughput screening identifies Ceefourin-1 and Ceefourin-2 as highly selective inhibitors of multidrug resistance protein 4 (MRP4). Biochem. Pharmacol. 91: 97-108 (2014).
  5. D. Jin, T.T. Ni, J. Sun, H. Wan, J.D. Amack, G. Yu, J. Fleming, C. Chiang, W. Li, A. Papierniak, S. Cheepala, G. Conseil, S.P.C. Cole, B. Zhou, I.A. Drummond, J.D. Schuetz, J. Malicki and T.P. Zhong. Prostaglandin signaling regulates ciliogenesis by modulating intraflagellar transport. Nat. Cell. Biol. 16: 841-851 (2014).  [Highlighted in News & Views, P. Barbry, L.E. Zaragosi. An ABC of ciliogenesis. Nat. Cell Biol. 16: 826-827 (2014)].
  6. S.P.C. Cole. Multidrug Resistance Protein 1 (MRP1, ABCC1): a "multitasking ABC transporter". J. Biol. Chem. 289: 30880-30888 (2014). (invited review)