Publications

RECENT PUBLICATIONS

Badham HJ, LeBrun DP, Rutter A, Winn LM: Transplacental benzene exposure increases tumor incidence in mouse offspring: possible role of fetal benzene metabolism. Carcinogenesis 31:1142, 2010

Lee AF, Hayes MM, LeBrun D, Espinosa I, Nielsen GP, Rosenberg AE, Lee C-H: FLI-1 distinguishes Ewing sarcoma from small cell osteosarcoma and mesenchymal chondrosarcoma. Appl Immunohistochem Mol Morphol 19:233, 2011

Alhejaily A, Wood B, Foster CJ, Farmer PL, Gilks CB, Brettschneider J, Day AG, Feilotter HE, Baetz T, LeBrun DP: Differential expression of cell cycle regulatory proteins defines distinct classes of follicular lymphoma. Hum Pathol 42:972, 2011

Varma S, LeBrun D. Striking mimicry of follicular lymphoma by a case of mantle cell lymphoma: a potential diagnostic pitfall. Can J Pathol 3(4):28, 2011

Yusuf D, Butland SL, Swanson MI, Bolotin E, Ticoll A, Cheung WA, Zhang XY, Dickman CT, Fulton DL, Lim JS, Schnabl JM, Ramos OH, Vasseur-Cognet M, de Leeuw CN, Simpson EM, Ryffel GU, Lam EW, Kist R, Wilson MS, Marco-Ferreres R, Brosens JJ, Beccari LL, Bovolenta P, Benayoun BA, Monteiro LJ, Schwenen HD, Grontved L, Wederell E, Mandrup S, Veitia RA, Chakravarthy H, Hoodless PA, Mancarelli M, Torbett BE, Banham AH, Reddy SP, Cullum RL, Liedtke M, Tschan MP, Vaz M, Rizzino A, Zannini M, Frietze S, Farnham PJ, Eijkelenboom A, Brown PJ, Laperriere D, Leprince D, de Cristofaro T, Prince KL, Putker M, Del Peso L, Camenisch G, Wenger RH, Mikula M, Rozendaal M, Mader S, Ostrowski J, Rhodes SJ, Van Rechem C, Boulay G, Olechnowicz SW, Breslin MB, Lan MS, Nanan KK, Wegner M, Hou J, Mullen RD, Colvin SC, Noy PJ, Webb CF, Witek ME, Ferrell S, Daniel JM, Park J, Waldman SA, Peet DJ, Taggart M, Jayaraman PS, Karrich JJ, Blom B, Vesuna F, O'Geen H, Sun Y, Gronostajski RM, Woodcroft MW, Hough MR, Chen E, Europe-Finner N, Karolczak-Bayatti M, Bailey J, Hankinson O, Raman V, LeBrun DP, Biswal S, Harvey CJ, Debruyne JP, Hogenesch JB, Hevner RF, Heligon C, Luo XM, Blank MC, Millen KJ, Sharlin DS, Forrest D, Dahlman-Wright K, Zhao C, Mishima Y, Sinha S, Chakrabarti R, Portales-Casamar E, Sladek FM, Bradley PH, Wasserman WW. The transcription factor encyclopedia. Genome Biol 13:R24, 2012

 Hyndman BD, Denis CM, Bayly R, Thompson P, Smith SP, LeBrun DP: Mapping acetylation sites in E2A identifies a conserved lysine residue in activation domain 1 that promotes CBP/p300 recruitment and transcriptional activation. Biochim Biophys Acta 1819(5):375-81, 2012

Hyndman BD, Bayly R, Cote GP, LeBrun DP: E2A proteins enhance the histone acetyltransferase activity of the transcriptional co-activators CBP and p300. Biochim Biophys Acta 1819(5):446-53, 2012

Denis CM, Chitayat S, Plevin MJ, Wang F, Thompson P, Liu S, Spencer HL, Ikura M, LeBrun DP, Smith SP: Structural basis of CBP/p300 recruitment in leukemia induction by E2A-PBX1. Blood 120(19):3968, 2012

Wood B, Sikdar S, Choi SJ, Virk S, Alhejaily A, Baetz T, LeBrun DP: Abundant expression of IL-21 receptor in follicular lymphoma cells is associated with more aggressive disease. Leuk Lymphoma 54(6):1212, 2013

Goswami RS, Atenafu EG, Xuan Y, Waldron L, Pintor dos Reis P, Sun T, Datti A, Xu W, Kuruvilla J, Good DJ, Lai R, Church AJ, Lam W, Baetz T, LeBrun DP, Sehn LH, Farinha P, Jurisica I, Bailey DJ, Gascoyne RD, Crump M, Kamel-Reid S. A microRNA signature obtained from the comparison of aggressive to indolent non-Hodgkin lymphomas can be used in the prognosis of mantle cell lymphoma. J Clin Oncol 31(23):2903, 2013

Alhejaily A, Day AG, Feilotter HE, Baetz T, LeBrun DP: Inactivation of the CDKN2A tumour suppressor gene by deletion or methylation is common at diagnosis in follicular lymphoma and associated with poor clinical outcome. Clin Cancer Res, 20(6):1676, 2014

Denis CM, Langelaan DN, Kirlin AC, Chitayat S, Munro K, Spencer HL, LeBrun DP, Smith SP: Functional redundancy between the transcriptional activation domains of E2A is mediated by binding to the KIX domain of CBP/p300. Nucleic Acids Res 42(11):7370, 2014

Ghaffari A, Hoskin V, Szeto A, Hum M, Liaghati N, Nakatsu K, LeBrun D, Madarnas Y, SenGupta S, Elliott B. A novel role for ezrin in breast cancer angio/lymphangiogenesis. Breast Cancer Res 16(5):438, 2014 

Leduc C, P Blandino II, Alhejaily A, Baetz T, Good DJ, Farmer PL, Squire JA, LeBrun DP: Composite mantle cell and primary cutaneous anaplastic large cell lymphoma: case report and review of the literature. Am J Dermatopathol 37(3):232, 2015

Graham C, LeBrun DP: Tumor suppressors in follicular lymphoma. Leuk Lymphoma 14:1, 2015

Sangrar W, Shi C, Mullins G, LeBrun D, Ingalls B, Greer PA: Amplified Ras-MAPK signal states correlate with accelerated EGFR internalization, cytostasis and delayed HER2 tumor onset in Fer-deficient model systems. Oncogene, 34(31):4109, 2015

Woodcroft M, Nanan K, Thompson P, Tyryshkin K, Smith SP, Slany R, LeBrun DP: Retrovirus-mediated expression of E2A-PBX1 blocks lymphoid fate but permits retention of myeloid potential in early hematopoietic progenitors. PLoS One 10(6):e0130495, 2015

Zhang CS, Kim H, Mullins G, Tyryshkin K, LeBrun D, Elliott BE, Greer PA. J Clin Cell Immunol 6:329, 2015