My lab studies tyrosine kinase signaling pathways that regulate cell motility, tissue invasion and inflammation. We currently have projects focusing on mast cells, that produce a wide array of mediators that can remodel tissues during immune responses and regulate tumour progression. We also study contributions of F-BAR proteins in metastatic cancers using cell and mouse models.
“Currently seeking qualified PhD students with interest in cancer therapeutic development” (02 May 2017).
Defining targets and new therapies in metastatic cancers
The Craig lab has several projects related to molecular mechanisms of cancer progression, immune suppression, and metastasis:
- Tumour suppressor miRNA targets and pathways
- Developing new tools to target actin-driven cancer metastasis
- Targeting immune suppression pathways in metastatic cancers
- Functional genomic screening to identify vulnerabilities in inflammatory breast cancer
- Defining circulating miRNA biomarkers in lung cancer patients treated with immunotherapy
Interested in joining the team, or to get more information, contact firstname.lastname@example.org
Our research in the news:
- https://globalnews.ca/video/4825019/there-is-exciting-research-coming-out-of-queens-university-when-it-comes-to-stopping-the-spread-of-cancer (7 Jan/19)
- CBC All in a Day interview (4 Jan/19)
This research has been made possible by current or former support from Queen’s University Research Opportunities Fund, Canadian Institutes for Health Research, Cancer Research Society, and Canadian Cancer Society Research Institute.